2018 REU Students
Research Experiences for Undergraduates (REU) Group 2018
Undergraduate Institution: BYU Idaho
Faculty Advisor: Professor Savage
Research: This summer I investigated the synergistic activity of antifungal compounds and ceragenins.
More specifically, under the direction of Dr. Savage I have developed non-peptide mimics of antimicrobial peptides (AMPs) to take advantage of the antimicrobial mechanism of AMPs without their limitations as clinical therapeutics. CSA-131 have been shown to exhibit synergistic effects with lower drugs in the past. For this reason, we felt they had potential to also act in synergy with caspofungin or amphotericin B. We ran synergy tests between CSA-131 and these two antifungals in order to assess the degree of synergy between them.
Undergraduate Institution: Utah State University
Faculty Advisor: Professor Hansen
Research: Under the direction of Professor Hansen I worked with an anaerobic digester to produce methane gas as a renewable energy source.
Undergraduate Institution: Leeward Community College
Faculty Advisor: Professor Austin
Research: During this summer I continued the development of paper spray mass spectrometry by investigating holder designs generated with 3D printing.
Undergraduate Institution: University of Hawaii
Faculty Advisor: Professor Ess
Research: I used density functional theory computational methods to model and predict the reactivity of Sn high-oxidation state complexes for alkane and arene C-H activation and functionalization reactions.
Undergraduate Institution: Northern Arizona
Faculty Advisor: Professor Christensen
Research: The Christensen lab studies the role of capillary morphogenesis gene 2 (CMG2) in angiogenesis. Throughout the summer, I focused on how extracellular matrix proteins interact with CMG2 by synthesizing fragments of matrix proteins and testing them using biolayer interferometry.
Undergraduate Institution: Snow College
Faculty Advisor: Professor Stowers
Research: I characterized nickel oxide ceria catalysts for ethane oxidative dehydrogenation. We doped nickel oxide catalysts with ceria and titanium to test the conversion and selectivity.
Undergraduate Institution: Western State Colorado University
Faculty Advisor: Professor Woodfield
Research: I worked on the transformation of powder silica doped alumina to a hardened tri-lobe with the goal to make Fischer-Tropsch catalysts more efficient by optimizing the surface area, pore volume, and pore diameter.
Undergraduate Institution: University of Utah
Faculty Advisor: Professor Linford
Research: The Linford lab focuses on material science and my summer research focused on the surface analysis of glass using time-of-flight secondary ion mass spectrometry (ToF-SIMS). ToF-SIMS technique is important because we are able to analyze the outer 1-2 nanometers of the glass surface which is where all the chemistry occurs. We specifically examined SiOH+/Si+ to quantify how much surface hydroxylation took place after we chemically treated the glass surface.
Undergraduate Institution: BYU Hawaii
Faculty Advisor: Professor Castle
Research: Simply put, I worked on synthesizing a tetrapeptide and substituting the amino acids with dehydro amino acids to increase the peptide stability.
More specifically, I worked on forming tetrapeptide and substituting the Amino Acids with dehyro A.A. to increase the stability of peptide. Once done making tetrapeptide, various test are tested on it by using 2D NMR, X-ray crystallography, and proteolysis to determine the structure and stability of the peptide. If successful in increasing stability, it can be used for peptide pharmaceuticals to help the metabolism not proteolysis the peptide as quickly.
Undergraduate Institution: Dixie State University
Faculty Advisor: Professor Woolley
Research: This summer is optimized fluorescent labeling and 3D printed microfluidic devices.
The purpose of this project is to develop a diagnostic test for pregnant women testing for premature labor. I worked on the optimization of Labeling florescence isothiocyanate to amino acids. This will help us make labeling florescence isothiocyanate more efficient when labeling proteins and peptides that stand has bio-markers for preterm birth risk. I also found a set of conditions in a micro-fluidic device that will support a voltage separation of these protein bio-markers.